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2.25ml auto-injector by Savicred, featuring Covestro's medical-grade Makrolon® polycarbonates
Case study

Material Innovation Enables Advanced Biologics Auto-Injector

When Savicred sought to develop a 2.25ml auto-injector for high-volume biologics delivery, our high-performance materials provided the solution. The Savicred collaboration successfully addressed key technical challenges while enabling reliable patient-friendly drug delivery, demonstrating how innovation in healthcare materials can advance drug delivery systems.
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Task

Meeting New Demands in Biologics Delivery

The biologics market is shifting toward higher-volume medication delivery systems to reduce injection frequency and enable home treatment. Savicred needed to develop a 2.25ml biologics injector that could reliably handle larger volumes and more viscous formulations while ensuring patient safety and ease of use. This required biocompatible materials that could meet stringent performance requirements without compromising manufacturability.

The advanced drug delivery systems space presents tremendous opportunities for innovation as the industry moves toward more complex biologics and patient-friendly drug delivery. As a leading provider of innovative medical materials, we enable manufacturers to develop more advanced, reliable auto-injector solutions that ultimately improve the treatment experience for patients.

Nan Hu

Global Vice President for Sales and Market Development Healthcare, Engineering Plastics, Covestro

Challenge

Overcoming Material and Design Challenges

Developing auto-injector solutions for high-volume biologics delivery presents complex design and material challenges. This meant addressing multiple critical requirements at the same time: maintaining strength in load-bearing components under injection forces, achieving structural integrity in ultra-thin walls (≤1.0mm) to enable compact design, providing clear visibility of the drug solution, and meeting strict biocompatibility requirements for patient safety, all while supporting efficient manufacturing of complex components.

Solution

Materials Enabling Advanced Drug Delivery Systems

Our high-performance, biocompatible medical materials, including Makrolon® 2458, enable the part strength, structural integrity, and dimensional stability of auto injectors – ensuring accurate dosing and easy handling for better patient compliance. Their unique combination of properties enables strong yet compact designs with ultra-thin walls, while the exceptional clarity of our polycarbonates allows complete visibility of the drug solution, a critical feature for patient safety and compliance. These innovative medical materials also offer superior processability that enables efficient manufacturing of complex components, allowing Savicred to develop a 2.25ml biologics delivery device that meets the growing demand for high-volume administration of biologics while supporting patient self-administration.

The next-generation auto-injector by Savicred enables reliable high-volume biologics delivery.

As we push the frontiers of biologics delivery, material innovation is pivotal. The solutions from Covestro provide the durability, consistency, and safety we need to develop biologics auto-injectors that can enhance patient convenience and support treatment adherence at home. Our partnership demonstrates how material innovation can advance medication delivery systems.

Xiao Lin

CEO, Savicred Biotechnology Co., Ltd.

Key benefits

  • Performance: Advanced material properties ensure reliable drug delivery under higher pressures and volumes while maintaining dimensional stability.
  • Patient safety: Medical-grade materials with proven biocompatibility and chemical stability support safe and consistent drug administration.
  • Manufacturing edge: Superior processability enables efficient production of complex components with high precision and consistency.
  • Design freedom: Material versatility allows device designers to optimize component geometry while achieving both superior clarity and thin-wall designs.

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